Overview
TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring 43-amino-acid peptide found in nearly all human tissues. It promotes cell migration, wound healing, and anti-inflammatory responses. Often used in combination with BPC-157 for injury recovery protocols.
Mechanism of action
TB-500 upregulates actin, a cell-building protein essential for cell migration and tissue repair. It promotes angiogenesis, reduces inflammation by downregulating inflammatory cytokines, and has demonstrated cardioprotective effects in animal models by reducing scar formation after cardiac injury.
Dosing protocols
| Purpose | Route | Dosage | Frequency | Notes |
|---|---|---|---|---|
| injury recovery | subcutaneous | 2–5 mg | twice weekly | Loading phase: 2-5mg 2x/week for 4-6 weeks. Maintenance: 2mg 2x/month. |
Dosing information is for educational purposes only. Consult a qualified healthcare professional before using any peptide.
Research summary
Preclinical studies show accelerated wound healing, reduced cardiac scar tissue, and improved neurological recovery after brain injury. Used extensively in veterinary medicine (particularly racehorses). Limited human clinical data; most evidence comes from animal studies and case reports.
Side effects
Side effects vary by individual. This is not an exhaustive list. Report unusual symptoms to a healthcare professional.
Common stacks
Peptides commonly paired with TB-500 for synergistic effects.
Legal status
Under FDA reclassification review. Previously classified as a research chemical. Widely used in veterinary medicine.
Where to get it
Verified directory — coming soon
PeptaHub is building a verified supplier directory with third-party testing data, compliance status, and reader ratings. Supplier listings will be available if FDA reclassification is formalized.